Aviation biofuel made from tobacco? That's what Boeing, South African Airways and SkyNRG are collaborating on. 

By using hybrid tobacco, we can leverage knowledge of tobacco growers in South Africa to grow a marketable biofuel crop without encouraging smoking

SkyNRG is the company that provides the biofuel for KLM's initiative. The airline uses used cooking oil-based fuel in a B777 between JFK and AMS and in a A330 between AUA and AMS. Boeing has been investing in biofuels for quite some time, with a recent focus on algae-based ones. The B747 was the first civil jetliner to have flown with such a mixture (it was coconut-based and the airline was Virgin Atlantic, back in 2008).